FlyBase Allele Report: Dmel\stumps[ems7]

General Information

Symbol

Dmel\stumps^ems7

Species

D. melanogaster

Name

FlyBase ID

FBal0094524

Feature type

allele

Associated gene

Dmel\stumps

Associated Insertion(s)

Carried in Construct

Also Known As

hbr^ems7

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Michelson et al., 1998)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

embryonic/larval dorsal tracheal branch

(Zhu et al., 2005)

embryonic/larval tracheal system

(Michelson et al., 1998)

Detailed Description

Statement

Reference

Stage 14-15 mutant embryos show defects in dorsal branch formation in the tracheal system; 11% are missing.

(Zhu et al., 2005)

Homozygous embryos have tracheal defects similar to those seen in stumps^YY202 embryos.

(Michelson et al., 1998)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhanced by

Statement

Reference

stumps^ems7 has embryonic/larval dorsal tracheal branch phenotype, enhanceable by robo2⁸

(Zhu et al., 2005)

stumps^ems7 has embryonic/larval dorsal tracheal branch phenotype, enhanceable by Sar1^EP3575

(Zhu et al., 2005)

NOT Enhanced by

Statement

Reference

stumps^ems7 has embryonic/larval dorsal tracheal branch phenotype, non-enhanceable by Dlc90F^EP3634

(Zhu et al., 2005)

stumps^ems7 has embryonic/larval dorsal tracheal branch phenotype, non-enhanceable by ball^EP863

(Zhu et al., 2005)

stumps^ems7 has embryonic/larval dorsal tracheal branch phenotype, non-enhanceable by dco^EP3280

(Zhu et al., 2005)

NOT suppressed by

Statement

Reference

stumps^ems7 has embryonic/larval dorsal tracheal branch phenotype, non-suppressible by Dlc90F^EP3634

(Zhu et al., 2005)

stumps^ems7 has embryonic/larval dorsal tracheal branch phenotype, non-suppressible by ball^EP863

(Zhu et al., 2005)

stumps^ems7 has embryonic/larval dorsal tracheal branch phenotype, non-suppressible by dco^EP3280

(Zhu et al., 2005)

Additional Comments

Genetic Interactions

Statement

Reference

lea^robo2-8 enhances the defects in dorsal branch formation seen in stumps^ems7 embryos; in the double mutant 71% are missing and 8% are stalled. sar1^EP3575 enhances the defects in dorsal branch formation seen in stumps^ems7 embryos; in the double mutant 31% are missing and 5% are stalled. In addition, 24.5% of the double mutant embryos show defects in germ-band retraction.

(Zhu et al., 2005)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

stumps^YY202

(Michelson et al., 1998)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

hbr^ems7

(Zhu et al., 2005, Michelson et al., 1998)

stumps^ems7

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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