A chimeric construct in which the tin homeodomain has been replaced by the Mmus\Nkx2-5 homeodomain and NK2-specific domain is expressed under the control of an Hsp70 promoter.
tin::Mmus\Nkx2-52.5HD-NK2SD.hs is a suppressor of embryonic/larval pericardial cell phenotype of tinEC40
Restores the formation of pericardial cells when expressed in tinEC40 embryos at 3.5 to 4.5 hours of development, although the cells are in a disorganised pattern.
Assayed in D.melanogaster.