FB2024_03 , released June 25, 2024
Allele: Dmel\yrh1
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General Information
Symbol
Dmel\yrh1
Species
D. melanogaster
Name
FlyBase ID
FBal0091070
Feature type
allele
Associated gene
Dmel\y
Associated Insertion(s)
gypsy{}y-2
gypsy{}y-rh1-a
H{}y-dh1-a
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
hobo dysgenesis
(Gause et al., 1998)
Progenitor genotype
ydh1
(Gause et al., 1998)
y2
(Melnikova et al., 2002)
Associated Insertion(s)
gypsy{}y-2
gypsy{}y-rh1-a
H{}y-dh1-a
H{}y-dh1-b
H{}y-rh1-b
Cytology
Description

hobo elements have inserted into the wing enhancer of y and the first intron of y : the region between these two hobo elements has been duplicated, such that the resulting structure is: hobo in wing enhancer - gypsy of y2 (at -700bp) - y first exon - hobo in wing enhancer - gypsy of y2 (at -700bp) - y first exon - hobo insertion - rest of y.

(Melnikova et al., 2002)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      macrochaeta & adult thorax

      (Gause et al., 1998)

      macrochaeta & leg

      (Gause et al., 1998)
      Detailed Description
      Statement
      Reference

      Body colour: Wild type pigmentation of body cuticle and wing blade.

      (Melnikova et al., 2002)

      Body color score: 5 Wing color score: 5 Thoracic bristle color score: 1 Leg bristle color score: 2 Wing bristle color score: 5 Abdomen bristle color score: 5

      (Gause et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      yrh1 has phenotype, enhanceable by mod(mdg4)ul

      (Gause et al., 1998)
      Suppressed by
      Statement
      Reference

      yrh1 has phenotype, suppressible by su(Hw)2

      (Gause et al., 1998)

      yrh1 has phenotype, suppressible by su(Hw)V

      (Gause et al., 1998)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      The duplication of the body and wing enhancers, gypsy and y promoter has led to the restoration of y expression in the body and wing.

      (Melnikova et al., 2002)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      yrh1
      Name Synonyms
      Secondary FlyBase IDs
        References (2)