FB2024_03 , released June 25, 2024
Allele: Dmel\hthP1-K6-1
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General Information
Symbol
Dmel\hthP1-K6-1
Species
D. melanogaster
Name
FlyBase ID
FBal0089225
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Cytology
Description

Excision of the P{lacW} element.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygous clones in ventral head tissue result in ectopic eye formation, some of which are at the tip of a tubular outgrowth. Clones within the compound eye or dorsal head structures do not show morphological phenotypes. The eye shape may be distorted when homozygous clones cross the eye border. Ectopic photoreceptor differentiation and local outgrowth can be seen in the eye-antenna discs of late third instar larvae bearing homozygous clones. These ectopic photoreceptors are only found in the ventral margin of the disc, and clones in the dorsal margin of the disc do not induce ectopic photoreceptor development. Homozygous clones in the second or third antennal segments result in transformation to leg-like structures, with larger clones producing a clear claw structure indicative of a distal leg. Clones in the coxa, femur or tibia often cause fusion of these leg segments, whereas clones in the tarsal segments are morphologically normal. Clones in the mesonotum and abdomen do not have significant morphological phenotypes.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (4)