FB2024_03 , released June 25, 2024
Allele: Dmel\Doas2784
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General Information
Symbol
Dmel\Doas2784
Species
D. melanogaster
Name
FlyBase ID
FBal0087040
Feature type
allele
Associated gene
Dmel\Doa
Associated Insertion(s)
P{lacW}Doas2784
Carried in Construct
Also Known As
l(3)s2784
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(BDGP Project Members, 1994-1999)
Progenitor genotype
Associated Insertion(s)
P{lacW}Doas2784
Cytology
Description

The P{lacW} element is inserted 126 nucleotides 5' to the first non-coding exon of the 105kDa Doa coding transcript and 1662 nucleotides 5' to its initiating AUG.

(Kpebe and Rabinow, 2008)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      In DoaHD/Doas2784 mutants where the DoaHD allele is from the mother blackened areas are seen on the wings. When the Doas2784 allele comes from the mother the mutants die at or prior to the pupal stage.

      (Kpebe and Rabinow, 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Precise excision of the P{lacW} element produces flies that are viable in combination with either DoaHD or Doa3B.

      (Kpebe and Rabinow, 2008)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Doas2784
      l(3)s2784
      (Spradling et al., 1999)
      l(3)s2784s2784
      Name Synonyms
      Secondary FlyBase IDs
        References (3)