FB2024_03 , released June 25, 2024
Allele: Dmel\acd(2)5D105D10
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General Information
Symbol
Dmel\acd(2)5D105D10
Species
D. melanogaster
Name
FlyBase ID
FBal0086732
Feature type
allele
Associated gene
acd(2)5D10
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Eberl et al., 1997)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      acd(2)5D105D10 homozygous larvae have reduced touch sensitivity compared to wild-type. Locomotion in these larvae is mildly aberrant: They are slower and change direction more often than controls. These defects in locomotion arise at least partially from defective peristaltic motion: stride period and % positive and negative flow are altered compared to wild-type. Despite their locomoter defects, these larvae exhibit normal phototaxic behaviour.

      (Caldwell et al., 2003)

      Audiograms demonstrate mutants show a reduced response at all sound intensity.

      (Eberl et al., 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      5D10
      (Ejima and Griffith, 2008)
      acd(2)5D105D10
      Name Synonyms
      Secondary FlyBase IDs
        References (3)