Germ cell migration occurs normally in mutant embryos and the germ cells are able to correctly associate with the gonadal mesoderm. However, the germ cells fail to form the tight cluster typically found in a properly coalesced gonad and instead remain loosely aligned. Mutants die at the end of embryogenesis, with no general defects in the nervous system, midgut, musculature or cuticle pattern.
Fas2-positive nerve bundles frequently cross the midline in mutant embryos, in contrast to wild-type.
Mutants exhibit failure of the ability of germ cells and the gonadal mesoderm to coalesce into the embryonic gonad. Very late stage embryos exhibit germ cells and somatic gonadal precursors (SGPs) remaining in a line, instead of the characteristic round shape of the gonads by stage 14. The SGPs appear as if they are incapable of making close contacts with one another.
foiunspecified has symmetrical commissure phenotype, enhanceable by pntunspecified
foiunspecified has symmetrical commissure phenotype, enhanceable by α-Specunspecified
foiunspecified is an enhancer of symmetrical commissure phenotype of pntunspecified
foiunspecified is an enhancer of symmetrical commissure phenotype of α-Specunspecified
foiunspecified pntunspecified or foiunspecified klounspecified double mutant embryos show a slightly enhanced fused commissure phenotype compared to the phenotypes of the single mutants. The number of midline glial cells is reduced in the double mutant embryos.
foiunspecified is rescued by Scer\GAL4unspecified/foiUAS.cPa
3 mutants are isolated.