FB2024_03 , released June 25, 2024
Allele: Dmel\tupunspecified
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General Information
Symbol
Dmel\tupunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0086278
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Homozygous clones on the metanotum can give rise to an ectopic structure that has pedicel-like sensilla campaniformia at its base (these sensory structures are normally found in the basal part of the haltere). Homozygous clones can also give rise to invaginations of the notum cuticle, and some of these invaginations have trichomes and hinge-like sensilla campaniformia.

    Mutants show no overt defects in the overall architecture of the CNS.

    tupunspecified mutant embryos have a broad head. Germ band shortening ceases early, resulting in the three most posterior segments remaining on the dorsal side of the embryo.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
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    Suppressor of
    Statement
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    Other
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    In tupunspecified, exexunspecified double mutants the scaffold of CNS axons is aberrant, the commissures are often greatly reduced or absent. ISNb projections clump in the proximity of the ISN. Axons within the ISN defasciculate aberrantly and ISNs from adjacent hemisegments can fuse across the parasegment boundary.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    tupunspecified
    Name Synonyms
    Secondary FlyBase IDs
      References (4)