FB2024_03 , released June 25, 2024
Allele: Dmel\DeltaS.GMR.Tag:MYC
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General Information
Symbol
Dmel\DeltaS.GMR.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0083549
Feature type
allele
Associated gene
Dmel\Delta
Associated Insertion(s)
Carried in Construct
P{GMR-Delta.S}
Key Links
Transgenic product class
stop_gained
(Sun and Artavanis-Tsakonas, 1997)
Mutagen
Nature of the Allele
Transgenic product class
stop_gained
(Sun and Artavanis-Tsakonas, 1997)
Mutagen
in vitro construct
(Sun and Artavanis-Tsakonas, 1997)
Progenitor genotype
Carried in construct
P{GMR-Delta.S}
Cytology
Description

A stop codon has been inserted just C-terminal to the last EGF-like repeat, approximately 20 amino acids upstream of the transmembrane domain. Three copies of Tag:MYC have been added to the carboxy-terminus, and expression is driven by a GMR promoter.

(Sun and Artavanis-Tsakonas, 1997)
Allele components
Component
Use(s)
Regulatory region(s)
GMR
Encoded product / tool
Delta
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Rough eye phenotype. Irregular ommatidial shape, occasional ommatidial fusion, duplication of bristles. Number of photoreceptor cells is normal, but pigment cells are lost reflecting ommatidial fusion. Phenotype is enhanced by loss of function Dl and gain of function Su(H) mutations.

      (Sun and Artavanis-Tsakonas, 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      DeltaS.GMR.Tag:MYC
      DlS.GMR.T:Hsap\MYC
      DlS.GMR.T:Myc
      DlS.GMR.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (1)