FB2024_03 , released June 25, 2024
Allele: Ecol\lacZHsrω.498
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General Information
Symbol
Ecol\lacZHsrω.498
Species
E. coli
Name
FlyBase ID
FBal0062678
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
Carried in Construct
P{498lacZ}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Mutsuddi and Lakhotia, 1995)
Progenitor genotype
Ecol\lacZhs43
(Mutsuddi and Lakhotia, 1995)
Carried in construct
P{498lacZ}
Cytology
Description

498bp fragment of lncRNA:Hsrω upstream sequences from -850 to -347 (lacking the TATA box and transcription start site) drives expression of Ecol\lacZhs43.

(Mutsuddi and Lakhotia, 1995)
Allele components
Component
Use(s)
Encoded product / tool
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage
      embryonic/larval brain
      (Mutsuddi and Lakhotia, 1995)
      larval ventral nerve cord
      (Mutsuddi and Lakhotia, 1995)
      prothoracic gland
      (Mutsuddi and Lakhotia, 1995)
      imaginal disc
      (Mutsuddi and Lakhotia, 1995)
      adult stage
      adult optic lobe
      (Mutsuddi and Lakhotia, 1995)
      wing | restricted
      (Mutsuddi and Lakhotia, 1995)
      testis | restricted
      (Mutsuddi and Lakhotia, 1995)
      oogenesis
      follicle cell
      (Mutsuddi and Lakhotia, 1995)
      nurse cell
      (Mutsuddi and Lakhotia, 1995)
      Additional Information
      Statement
      Reference

      A EcollacZ reporterconstruct driven by a 498 bp distal Hsrω promoter is expressed at lowerlevels than that driven by a 844 bp promoter in imaginal discs, in the brainhemispheres and the ventral ganglia of third instar larvae. Expression isdetected in the nurse cell, and in the testis during mid-spermatogenesis.Expression is also detected in the prothoracic gland. Unlike wild-typeHsrω transcript, reporter construct expression is also detected in thewing blade, optic lobe, and follicle cells and oocytes of adult flies.

      (Mutsuddi and Lakhotia, 1995)
       
      Marker for
      Reflects expression of
      lncRNA:Hsrω
      (Mutsuddi and Lakhotia, 1995)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Ecol\lacZHsrω.498
      lacZHsr93D.498
      lacZHsrω.498
      Name Synonyms
      Secondary FlyBase IDs
        References (2)