FB2024_03 , released June 25, 2024
Allele: Dmel\mspoUAS.cUa
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General Information
Symbol
Dmel\mspoUAS.cUa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Umemiya
FlyBase ID
FBal0062551
Feature type
allele
Associated gene
Dmel\mspo
Associated Insertion(s)
Carried in Construct
P{UAS-mspo}
Key Links
Transgenic product class
cDNA
(Umemiya et al., 1997)
wild_type
(Umemiya et al., 1997)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Umemiya et al., 1997)
wild_type
(Umemiya et al., 1997)
Mutagen
in vitro construct
(Umemiya et al., 1997)
Progenitor genotype
Carried in construct
P{UAS-mspo}
Cytology
Description

UASt regulatory sequences drive expression of a 2.2kb NotI-KpnI fragment of mspo cDNA containing the entire open reading frame.

(Umemiya et al., 1997)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
mspo
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Overexpression of mspoScer\UAS.cUa in embryos under the control of Scer\GAL4eve.eme decreases the number of muscle nuclei, notably in DA1.

      Overexpression of mspoScer\UAS.cUa under the control of Scer\GAL4eve.eme reduces the fusion rate of embryonic myoblasts compared with wild-type.

      (Bataillé et al., 2010)

      Scer\GAL4how-24B-mediated expression in the muscles does not affect the morphology of these muscles or the formation of muscle insertions.

      (Umemiya et al., 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of Mp20Scer\UAS.cBa and mspoScer\UAS.cUa under the control of Scer\GAL4eve.eme restores the wild-type number of DA1 nuclei.

      Co-expression of PaxScer\UAS.cCa and mspoScer\UAS.cUa under the control of Scer\GAL4eve.eme restores the wild-type number of DA1 nuclei.

      (Bataillé et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      mspoScer\UAS.cUa
      mspoUAS.cUa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Umemiya
      (Umemiya et al., 1997)
      Secondary FlyBase IDs
        References (2)