FB2024_03 , released June 25, 2024
Allele: Dmel\spiunspecified
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General Information
Symbol
Dmel\spiunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0059934
Feature type
allele
Associated gene
Dmel\spi
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In

        abdominal 1 lateral pentascolopidial chordotonal organ lch5

        (Okabe and Okano, 1997)

        abdominal 1 ventral monoscolopidial chordotonal organ vch1

        (Okabe and Okano, 1997)

        abdominal 2 lateral pentascolopidial chordotonal organ lch5

        (Okabe and Okano, 1997)

        abdominal 2 ventral monoscolopidial chordotonal organ vch1

        (Okabe and Okano, 1997)

        abdominal 3 lateral pentascolopidial chordotonal organ lch5

        (Okabe and Okano, 1997)

        abdominal 3 ventral monoscolopidial chordotonal organ vch1

        (Okabe and Okano, 1997)

        abdominal 4 lateral pentascolopidial chordotonal organ lch5

        (Okabe and Okano, 1997)

        abdominal 4 ventral monoscolopidial chordotonal organ vch1

        (Okabe and Okano, 1997)

        abdominal 5 lateral pentascolopidial chordotonal organ lch5

        (Okabe and Okano, 1997)

        abdominal 5 ventral monoscolopidial chordotonal organ vch1

        (Okabe and Okano, 1997)

        abdominal 6 lateral pentascolopidial chordotonal organ lch5

        (Okabe and Okano, 1997)

        abdominal 6 ventral monoscolopidial chordotonal organ vch1

        (Okabe and Okano, 1997)

        abdominal 7 lateral pentascolopidial chordotonal organ lch5

        (Okabe and Okano, 1997)

        abdominal 7 ventral monoscolopidial chordotonal organ vch1

        (Okabe and Okano, 1997)

        anal pad

        (Tearle and Nusslein-Volhard, 1987)

        cephalopharyngeal skeleton

        (Tearle and Nusslein-Volhard, 1987)

        embryonic ventral nerve cord

        (Tearle and Nusslein-Volhard, 1987)

        Keilin organ

        (Tearle and Nusslein-Volhard, 1987)

        larval longitudinal connective

        (Hummel et al., 1999)

        larval sense organ & antennal segment

        (Tearle and Nusslein-Volhard, 1987)

        larval sense organ & maxillary segment

        (Tearle and Nusslein-Volhard, 1987)

        midline glial cell

        (Hummel et al., 1999)

        motor neuron

        (Hummel et al., 1999)

        presumptive embryonic/larval central nervous system

        (Hummel et al., 1999)

        presumptive embryonic/larval peripheral nervous system

        (Hummel et al., 1999)

        sensory neuron

        (Hummel et al., 1999)

        symmetrical commissure

        (Hummel et al., 1999)

        ventral denticle belt

        (Tearle and Nusslein-Volhard, 1987)
        Detailed Description
        Statement
        Reference

        Homozygous clones in the eye disc lead to normal R8 cell spacing.

        (Baonza et al., 2001)

        Mutant embryos show a clear fusion of commissures and frequent disruption of longitudinal connectives. Midline glial cells are either reduce in number or fail to properly migrate in between anterior and posterior commissures. General embryonic morphology is relatively normal, though the PNS shows a slight reduction in sensory neurons and defects in the trajectories of motoneurons.

        (Hummel et al., 1999)

        Homozygous embryos show a loss of 3 chordotonal organs per abdominal hemisegment (VChA and two in LCh5).

        (Okabe and Okano, 1997)

        spiunspecified mutant embryos have narrow denticle bands and the ventral arms of the head skeleton are fused. Anal pads, Keilin's organs, maxillary sense organs and antennal sense organs are reduced. The transverse commissure of the ventral nervous system are reduced. Semilethal in the germline.

        (Tearle and Nusslein-Volhard, 1987)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Enhancer of
        Statement
        Reference

        spiunspecified is an enhancer of eye phenotype of Scer\GAL4GMR.PF, nejΔBHQ.UAS

        (Anderson et al., 2005)
        Suppressor of
        Statement
        Reference

        spiunspecified, spi[+], Scer\GAL4Bx-MS1096 is a suppressor of wing vein | ectopic phenotype of Pstu\aarAUAS.cGa

        (Gallio et al., 2002)

        spiunspecified, spi[+], Scer\GAL4Bx-MS1096 is a suppressor of wing phenotype of Pstu\aarAUAS.cGa

        (Gallio et al., 2002)
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Fails to complement

        spis3547

        (Dworkin and Gibson, 2006)
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        spiunspecified
        unspecified
        (Okabe and Okano, 1997)
        Name Synonyms
        Secondary FlyBase IDs
          References (9)