FB2024_03 , released June 25, 2024
Allele: Dmel\UbxI.7
Open Close
General Information
Symbol
Dmel\UbxI.7
Species
D. melanogaster
Name
FlyBase ID
FBal0058032
Feature type
allele
Associated gene
Dmel\Ubx
Associated Insertion(s)
P{?'A92}UbxI.7
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Casares et al., 1997)
Mutagen
Delta2-3 transposase
(Casares et al., 1997)
Progenitor genotype
Ubxlac1
(Casares et al., 1997)
Associated Insertion(s)
P{?'A92}UbxI.7
Cytology
Description

Deletes from the site of the P{A92} insertion, -34kb of FBrf0040194, to -17kb, removing part of the first intron, the first exon and about 13kb upstream of the initiation site, including regions where several bithoraxoid mutations map. The Ecol\lacZ and ry+t7.2 are left intact.

(Casares et al., 1997)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      UbxI.7/Ubxbx-3 flies show a reduction of phenotype (increase of transvection) in the halteres when compared to Ubx1/Ubxbx-3 flies. However they show a stronger transformation than Ubx50.1/Ubxbx-3 flies. Ubx50.1/Ubxpbx-1 and UbxI.7/Ubxpbx-1 flies show a milder phenotype in the haltere than Ubx1/Ubxpbx-1 or Ubxpbx-1/Df(3R)P9, indicating there is transvection.

      (Casares et al., 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Attempts to mobilise the P{A92} with Δ2-3 failed, suggesting that one of the P-element sequences needed for mobilization has been impaired.

      (Casares et al., 1997)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ubx1.7
      (Duncan, 2002)
      UbxI.7
      Name Synonyms
      Secondary FlyBase IDs
        References (2)