FB2024_03 , released June 25, 2024
Allele: Ecol\lacZinsc-AB44
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General Information
Symbol
Ecol\lacZinsc-AB44
Species
E. coli
Name
FlyBase ID
FBal0050049
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Progenitor genotype
Associated Insertion(s)
Cytology
Description
Allele components
Component
Use(s)
Inserted element
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
distribution deduced from reporter
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference

Enhancer trapexpression is first detected at stage 6 in the procephalic neurectodermand later in the delaminating neuroblasts of the ventral nerve cord. Atlater embryonic stages, the EcollacZ pattern is stated to be the same as thepattern of insc protein which is as follows. In stage 10, expression isdetected in two cells per segment in the lateral epidermis that arethought to be the first two cells that will give rise to the larvalperipheral sense organs. Expression is lost in developing sense organs bythe time of dorsal closure but remains in the CNS until after it hascondensed. In stages 10-13, expression is seen in mesodermal cellspresumed to be muscle precursors and in the posterior midgut primordia.Strong expression is seen at stage 15 in the pharynx, gastric caecae,hindgut, tracheal branches, and Malpighian tubules. In ovaries, enhancertrap expression is observed in nurse cell-associated follicle cells. Instage S9, there is expression in follicle cells covering the anterior partof the oocyte and by stage 10, in the centripetal cells at the borderbetween the nurse cells and the oocyte.

 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Ecol\lacZinsc-AB44
lacZinsc-AB44
Name Synonyms
Secondary FlyBase IDs
    References (3)