FB2024_03 , released June 25, 2024
Allele: Dmel\wgPE13
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General Information
Symbol
Dmel\wgPE13
Species
D. melanogaster
Name
FlyBase ID
FBal0046804
Feature type
allele
Associated gene
Dmel\wg
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Bejsovec and Wieschaus, 1995)
Progenitor genotype
Cytology
Description

Amino acid replacement: W248term.

(Chao et al., 2003)

Nonsense mutation roughly halfway through the coding region at position 248. Amino acid replacement: W248@.

(Bejsovec and Wieschaus, 1995)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:7,314,392..7,314,392 [+]
Nucleotide change:

G7314392A

Amino acid change:

W248term | wg-PA

Reported amino acid change:

W248term

Comment:

A nonsense mutation in a Trp codon (TGG to TGA).

(Bejsovec and Wieschaus, 1995)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT suppressed by
      Statement
      Reference

      wgPE13 has phenotype, non-suppressible by eRF1[+]/eRF1F2

      (Chao et al., 2003)

      wgPE13 has ventral denticle belt | ectopic phenotype, non-suppressible by eRF3LR16/Elf[+]

      (Chao et al., 2003)

      wgPE13 has embryonic/first instar larval cuticle phenotype, non-suppressible by eRF1KY7/eRF1[+]

      (Chao et al., 2003)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The cuticle phenotype of wgPE13 homozygous embryos is not suppressed if their female parent is heterozygous for either eRF1KY7 or ElfLR16.

      (Chao et al., 2003)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      wgPE13
      Name Synonyms
      Secondary FlyBase IDs
        References (3)