Chromosomal females (XX) homozygous for tra2unspecified are transformed into "pseudomales". They are sterile even in the presence of a Y chromosome. The gonads form testes which are generally non-gametogenic, containing degenerated germ cells and debris or gonial cells whose sex cannot be determined. A variable proportion are gametogenic, containing either oogenic or spermatogenic stages of germ cell development (never both in the same gonad). In these cases oogenesis is arrested anywhere between stages S3 and S10A, and spermatogenesis is frequently arrested at the spermatocyte stage, although some later stages of spermatogenic differentiation are seen.
tra2[+]/tra2unspecified is an enhancer of abnormal sex-determination | dominant | female phenotype of dsxD
tra2unspecified dsxD XX double heterozygotes are more masculinised than dsxD heterozygotes.
