FlyBase Allele Report: Dmel\esc[10]

General Information

Symbol

Dmel\esc¹⁰

Species

D. melanogaster

Name

FlyBase ID

FBal0045608

Feature type

allele

Associated gene

Dmel\esc

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

amorphic allele - genetic evidence

Mutagen

Nature of the Allele

Allele class

amorphic allele - genetic evidence

(Campbell et al., 1995)

Mutagen

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Mutation does not affect the level of w expression in ph-p^lac+3 flies.

(Fauvarque et al., 1995)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

esc¹⁰/esc[+] is a suppressor of visible | dominant | homeotic phenotype of brm[+]/brm², trx^E2

(Gildea et al., 2000)

esc¹⁰/esc[+] is a suppressor of visible | dominant | homeotic phenotype of ash1¹⁷, trx^B11/trx[+]

(Gildea et al., 2000)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

esc¹⁰ has sex comb phenotype, non-enhanceable by HDAC1⁰⁴⁵⁵⁶

(Chang et al., 2001)

NOT suppressed by

Statement

Reference

esc¹⁰ has sex comb phenotype, non-suppressible by HDAC1⁰⁴⁵⁵⁶

(Chang et al., 2001)

NOT Enhancer of

Statement

Reference

esc¹⁰ is a non-enhancer of sex comb phenotype of HDAC1⁰⁴⁵⁵⁶

(Chang et al., 2001)

Suppressor of

Statement

Reference

esc¹⁰/esc[+] is a suppressor of adult prothoracic segment phenotype of E(z)^Trm

(Bajusz et al., 2001)

esc¹⁰/esc[+] is a suppressor of adult abdominal segment 4 | ectopic phenotype of E(z)^Trm

(Bajusz et al., 2001)

esc¹⁰/esc[+] is a suppressor of adult abdominal segment 5 phenotype of E(z)^Trm

(Bajusz et al., 2001)

esc¹⁰/esc[+] is a suppressor of adult mesothoracic segment | ectopic phenotype of E(z)^Trm

(Bajusz et al., 2001)

esc¹⁰/esc[+] is a suppressor of adult metathoracic segment phenotype of E(z)^Trm

(Bajusz et al., 2001)

esc¹⁰/esc[+] is a suppressor of adult metathoracic segment phenotype of brm[+]/brm², trx^E2

(Gildea et al., 2000)

esc¹⁰/esc[+] is a suppressor of adult metathoracic segment phenotype of ash1¹⁷, trx^B11/trx[+]

(Gildea et al., 2000)

NOT Suppressor of

Statement

Reference

esc¹⁰ is a non-suppressor of sex comb phenotype of HDAC1⁰⁴⁵⁵⁶

(Chang et al., 2001)

Additional Comments

Genetic Interactions

Statement

Reference

The addition of esc¹⁰ or E(z)⁶³ to Rpd3⁰⁴⁵⁵⁶ animals has no effect on the extra sex comb phenotype.

(Chang et al., 2001)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

esc¹⁰/esc² is rescued by esc^{lexA.αTub84B}

(Poux et al., 2001)

esc¹⁰/esc² is rescued by esc^lexA.hs

(Poux et al., 2001)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

esc¹⁰

(Huang et al., 2002, Fitzgerald and Bender, 2001)

Name Synonyms

Secondary FlyBase IDs

References (11)

Report Sections

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