FB2024_03 , released June 25, 2024
Allele: Dmel\dsxunspecified
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General Information
Symbol
Dmel\dsxunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0045542
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
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    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    The sexual size dimorphism of the control wing muscle hg1 is abolished in dsxunspecified null mutant. In contrast to wild-type, he size of the hg1 muscle in dsxunspecified mutant males is reduced relative to its size in females.

    XY dsxunspecified flies have intersexual external morphology.

    Chromosomal females (XX) mutant for dsx are transformed into "pseudomales". They are sterile even in the presence of a Y chromosome. The gonads form testes which are generally non-gametogenic, containing degenerated germ cells and debris or gonial cells whose sex cannot be determined. A variable proportion are gametogenic, containing either oogenic or spermatogenic stages of germ cell development (never both in the same gonad). In these cases oogenesis is arrested anywhere between stages S3 and S10A, and spermatogenesis is frequently arrested at the spermatocyte stage, although some later stages of spermatogenic differentiation are seen.

    External Data
    Interactions
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    Phenotypic Class
    NOT suppressed by
    Statement
    Reference
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    The intersexual external morphology of XY dsxunspecified flies is not altered by traF.Hsp83.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    dsxunspecified
    Name Synonyms
    Secondary FlyBase IDs
      References (5)