FlyBase Allele Report: Dmel\dpp[αTub84B.PZ]

General Information

Symbol

Dmel\dpp^αTub84B.PZ

Species

D. melanogaster

Name

α-Tubulin at 84B promoter construct of Zecca

FlyBase ID

FBal0045506

Feature type

allele

Associated gene

Dmel\dpp

Associated Insertion(s)

Carried in Construct

P{αTub84B(-FRT)dpp.Z}

Key Links

Transgenic product class

wild_type

(Zecca et al., 1995)

Mutagen

FLPase

Nature of the Allele

Transgenic product class

wild_type

(Zecca et al., 1995)

Mutagen

FLPase

(Dobens et al., 2000, Emerald and Roy, 1998, Kopp et al., 1997, Lecuit and Cohen, 1997, Zecca et al., 1995)

Progenitor genotype

dpp^{FRT.f.αTub84B}

(Dobens et al., 2000, Emerald and Roy, 1998, Kopp et al., 1997, Lecuit and Cohen, 1997, Zecca et al., 1995)

Carried in construct

P{αTub84B(-FRT)dpp.Z}

Cytology

Description

FRT cassette has been excised, juxtaposing αTub84B promoter with dpp coding sequences.

(Zecca et al., 1995)

Allele components

Component

Use(s)

Regulatory region(s)

αTub84B

Encoded product / tool

dpp

Also carries

FRT

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible

(Kopp et al., 1999, Emerald and Roy, 1998)

visible | somatic clone

(Kopp et al., 1999)

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of dpp^αTub84B.PZ results in disruptions in the follicle cell epithelium by stage 10B.

(Dobens et al., 2000)

Clones in the sternite or lateral tergite cause transformation of nearby tissue to pleural identity.

(Kopp et al., 1999)

Clones expressing dpp^αTub84B.PZ in the male external genitalia result in small duplications and not complete pattern reorganisation. They also show fusion of lateral lobes and claspers of both sides in the middle, leaving no opening to the exterior. All structures of the penis apparatus, except the hypandrium and the long and short bristles present on it, are absent. Clones in the vaginal plate result in duplication of the thorn and long bristles and fusion at the tip of the vaginal plate.

(Emerald and Roy, 1998)

Clones expressing dpp^αTub84B.PZ develop normally in most of the tergite.

(Kopp et al., 1997)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

dpp^αTub84B.PZ, nub¹ has visible phenotype