FB2024_03 , released June 25, 2024
Allele: Dmel\vvldfr-B1.57
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General Information
Symbol
Dmel\vvldfr-B1.57
Species
D. melanogaster
Name
FlyBase ID
FBal0044445
Feature type
allele
Associated gene
Dmel\vvl
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Anderson et al., 1996)
Mutagen
ethyl methanesulfonate
(Anderson et al., 1996)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous embryos exhibit a severely disrupted tracheal phenotype with limited tracheal cell migration and absence of primary branch formation. P{hs-btl.M} induced expression (45 minute heat shock at 4 hours of development) restores the normal tracheal phenotype; extensive cell migration and several well-defined branches, formation of dorsal trunk and restoration of lateral branches. Ventral nerve cord defects associated with mismigration of mesectodermal progeny are not rescued.

      (Anderson et al., 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Statement
      Reference

      vvldfr-B1.57 has visible | dominant phenotype, enhanceable by E(vvl)2323

      (Certel and Johnson, 1998)
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      vvldfr-B1.57 has wing vein phenotype, enhanceable by Mad[+]/MadE5

      (Certel and Johnson, 1998)

      vvldfr-B1.57 has wing vein phenotype, enhanceable by E(vvl)2323

      (Certel and Johnson, 1998)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      dfrB1.57
      (Anderson et al., 1995)
      dfrB157
      (Certel and Johnson, 1999, Certel et al., 1997, Anderson et al., 1996)
      vvldfr-B1.57
      vvldfrB157
      (Certel and Johnson, 1998, Certel and Johnson, 1998)
      Name Synonyms
      Secondary FlyBase IDs
        References (7)