FB2024_03 , released June 25, 2024
Allele: Dmel\rohs.PB
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General Information
Symbol
Dmel\rohs.PB
Species
D. melanogaster
Name
heat shock construct of Basler
FlyBase ID
FBal0044320
Feature type
allele
Associated gene
Dmel\ro
Associated Insertion(s)
Carried in Construct
P{hsp-rough}
Key Links
Transgenic product class
wild_type
(Basler et al., 1990)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Basler et al., 1990)
Mutagen
in vitro construct
(Basler et al., 1990)
Progenitor genotype
Carried in construct
P{hsp-rough}
Cytology
Description

Transcriptional fusion between the Hsp70 promoter/leader and a ro minigene lacking the two introns but comprising the entire open reading frame and the 3'-flanking sequences.

(Basler et al., 1990)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
ro
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Repeated heat induction at embryonic, larval and pupal stages results in lethality. Even single heat shock at the white prepupal stage cause a substantial reduction in survival. Hatched flies that survive the heat shock have reduced eyes bordered anteriorly by a vertical scar.

      (Basler et al., 1990)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      rohs.PB
      Name Synonyms
      heat shock construct of Basler
      (Basler et al., 1990)
      Secondary FlyBase IDs
        References (3)