FB2024_03 , released June 25, 2024
Allele: Dmel\repoEX84
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General Information
Symbol
Dmel\repoEX84
Species
D. melanogaster
Name
FlyBase ID
FBal0044311
Feature type
allele
Associated gene
Dmel\repo
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Halter et al., 1995)
Mutagen
Delta2-3 transposase
(Halter et al., 1995)
Progenitor genotype
repo03702
(Halter et al., 1995)
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      repoEX84/+ mutants exhibit significantly impaired long term memory performance 24 hours after spaced training in an aversive olfactory association paradigm, as compared to controls; but do not show significantly decreased anesthesia-resistant memory performance 24 hours after massed training in an aversive olfactory association paradigm, as compared to controls.

      (Matsuno et al., 2015)

      Late stage 14 embryos show disruptions in the axon scaffold. The projections of the VUM neurons are particularly affected. PNS phenotype is much weaker. AT later stages fibers are partially defasciculated. In mutant embryos of stage 17 the VNC remains extended to various degrees. The surface of the VNC in all mutant embryos has a very rough and loosely packed appearance. At the end of stage 12, the MM-CBG prematurely stop migrating. At this stage the number of glia in the VNC is wild type, but by stage 16 the total number of glial cells in the CNS is reduced.

      (Halter et al., 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      repo84
      (Trébuchet et al., 2019)
      repoEX84
      (Matsuno et al., 2019, Matsuno et al., 2015)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)