FB2024_03 , released June 25, 2024
Allele: Ecol\lacZ68-77
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General Information
Symbol
Ecol\lacZ68-77
Species
E. coli
Name
FlyBase ID
FBal0043828
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
P{lacZ}68-77
Carried in Construct
Also Known As
68-77
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Boyle et al., 1997, Boyle and DiNardo, 1995)
Progenitor genotype
Associated Insertion(s)
P{lacZ}68-77
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacZ}
Encoded product / tool
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage 13
      gonadal somatic stem cell
      (DeFalco et al., 2004)
      embryonic stage 13 -- 15
      gonad
      (Boyle et al., 1997)
      gonadal somatic stem cell
      (Boyle et al., 1997)
      embryonic stage 15
      gonadal somatic stem cell
      (DeFalco et al., 2003, Jenkins et al., 2003)
      gonad
      (DeFalco et al., 2003)
      gonadal sheath proper primordium
      (Jemc et al., 2012)
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage 11
      mesoderm | restricted
      (Boyle and DiNardo, 1995)
      parasegment 2 -- parasegment 14

      Comment: restricted expression

      (Boyle and DiNardo, 1995)
      embryonic stage 12
      gonadal sheath proper primordium
      (Boyle and DiNardo, 1995)
      embryonic stage 13
      gonad
      (Boyle and DiNardo, 1995)
      Additional Information
      Statement
      Reference

      Expression is observed in the somatic gonadal precursor cells.

      (DeFalco et al., 2004)

      Expression is observed in the gonadal mesoderm.

      (Jenkins et al., 2003)

      Expression is observed in all somatic cells of the embryonic gonad.

      (Boyle et al., 1997)

      Expression is first observed at embryonic stage 11, in patches in the mesoderm of parasegments 2-14, with higher expression in posterior parasegments 10-12. By embryonic stage 12, cells maintaining expression of lacZ appear to be moving anteriorly towards parasegment 10.

      (Boyle and DiNardo, 1995)
       
      Marker for
      gonadal sheath proper primordium
      (Boyle and DiNardo, 1995)
      somatic stem cell
      (DeFalco et al., 2004, DeFalco et al., 2003, Jenkins et al., 2003, Boyle et al., 1997)
      Reflects expression of
      Ubx
      (Boyle and DiNardo, 1995)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Ecol\lacZ expression occurs in the somatic cells of the newly formed gonad.

      (Boyle and DiNardo, 1995)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ecol\lacZ68-77
      lacZ68-77
      Name Synonyms
      Secondary FlyBase IDs
        References (8)