FB2024_03 , released June 25, 2024
Allele: Ecol\lacZSxl.Pe
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General Information
Symbol
Ecol\lacZSxl.Pe
Species
E. coli
Name
FlyBase ID
FBal0041988
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
Carried in Construct
P{SxlPe-lacZ}
Also Known As
Sxl-Pe:lacZ, Sxl-Pe:lac-Z, SxlPe:lacZ
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Estes et al., 1995, Keyes et al., 1992)
Progenitor genotype
Ecol\lacZC4.Adh
(Estes et al., 1995)
Carried in construct
P{SxlPe-lacZ}
Cytology
Description

5,289bp SalI-XhoI genomic fragment containing the Sxl-Pe start site as well as 3,651bp upstream and 1,629bp downstream are fused just upstream of lacZ.

(Estes et al., 1995)

Sxl embryonic promoter is fused to an Adh ::lacZ fusion gene.

(Keyes et al., 1992)
Allele components
Component
Use(s)
Regulatory region(s)
Sxl_early_embryonic_promoter
Encoded product / tool
lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      blastoderm stage | female
      somatic cell
      (Deshpande et al., 1999)
      organism | pair rule expression pattern
      (Vanderzwan-Butler et al., 2007)
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Sxl
      (Vanderzwan-Butler et al., 2007, Erickson and Cline, 1993)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      An increased sisA and sc dose equivalent to that in females cannot activate the construct P{SxlPe-lacZ} to the female expression level in all tissues.

      (Erickson and Cline, 1993)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ecol\lacZSxl.Pe
      lacZSxl.Pe
      Name Synonyms
      Secondary FlyBase IDs
        References (18)