FB2024_03 , released June 25, 2024
Allele: Ecol\lacZHsp70Bb.HZ50
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General Information
Symbol
Ecol\lacZHsp70Bb.HZ50
Species
E. coli
Name
FlyBase ID
FBal0041638
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
Carried in Construct
P{HZ50}
P{HZ50PL}
P{HZR}
Also Known As
HZ50PL
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Laval et al., 1993, Hiromi and Gehring, 1987)
Progenitor genotype
Carried in construct
P{HZ50}
P{HZ50PL}
P{HZ.w}
P{HZCaSpeR}
P{HZR}
Cytology
Description

Hsp70 promoter sequences drive Ecol\lacZ expression.

(Laval et al., 1993)

Construct: Hsp70 promoter sequences from position -50 to +271 (including the first 7 amino acids) are fused in frame to Ecol\lacZ, promoter sequences lack all of the heat shock elements shown to be required for heat inducibility.

(Hiromi and Gehring, 1987)
Allele components
Component
Use(s)
Encoded product / tool
Ecol\lacZ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference

      Of 22 independent transformed lines analyzed, most showed little, if any, β-gal expression. However, some lines did show exhibit various levels of expression, the pattern varying from line to line. Such expression was usually observed in late embyogenesis, however some lines showed expression along the ventral midline at germ-band extension.

      (Hiromi and Gehring, 1987)
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Ecol\lacZHsp70Bb.HZ50
      lacZHZ50
      lacZHsp70Bb.HZ50
      Name Synonyms
      Secondary FlyBase IDs
        References (71)