FB2024_03 , released June 25, 2024
Allele: Ecol\lacZCol4a1-A109.1F2
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General Information
Symbol
Ecol\lacZCol4a1-A109.1F2
Species
E. coli
Name
FlyBase ID
FBal0040972
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
P{lArB}Col4a1A109.1F2
Carried in Construct
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Bellen et al., 1989, Wilson et al., 1989)
Progenitor genotype
Associated Insertion(s)
P{lArB}Col4a1A109.1F2
Cytology
Description

P{lArB} insertion lies approximately 45bp upstream of the putative transcription start site of Cg25C.

(Wilson et al., 1989)
Allele components
Component
Use(s)
Inserted element
P{lArB}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      embryonic stage
      organism | ubiquitous
      (Matthews, 1995.11.17)
      embryonic stage 17
      embryonic/larval fat body
      (Bellen et al., 1989)
      hemocyte
      (Bellen et al., 1989)
      adult stage & oogenesis
      follicle cell
      (Bellen, 1998.8.10)
      Additional Information
      Statement
      Reference

      lacZ expression "essentially ubiquitous."

      (Matthews, 1995.11.17)

      In stage 17 embryos, expressed in fat body and in scattered cells, probably hemocytes. Mimics expression of Col4a1, except that β-galactosidase staining is first observed about 6 hours after Col4a1 transcripts are detected.

      (Wilson et al., 1989)
       
      Marker for
      embryonic/larval hemocyte
      (Yoshida et al., 2008)
      Reflects expression of
      Col4a1
      (Yoshida et al., 2008, Matthews, 1995.11.17, Bellen et al., 1989)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (3)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Reflects the expression pattern of Cg25C, although allelism has not been demonstrated.

      (Wilson et al., 1989)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Ecol\lacZCg25C-A109.1F2
      Ecol\lacZCol4a1-A109.1F2
      lacZCg25C-A109.1F2
      Name Synonyms
      Secondary FlyBase IDs
        References (10)