FB2024_03 , released June 25, 2024
Allele: Dmel\ifB6
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General Information
Symbol
Dmel\ifB6
Species
D. melanogaster
Name
FlyBase ID
FBal0039418
Feature type
allele
Associated gene
Dmel\if
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Bloor and Brown, 1998, Brown, 1994)
Mutagen
gamma ray
(Bloor and Brown, 1998, Brown, 1994)
Progenitor genotype
Caused by aberration
T(1;2)ifB6
Cytology
Description

Translocation break falls in the 2nd intron of if, separating the signal peptide and 1st 38 amino acids from the rest of the coding region.

(Brown, 1994)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Embryos exhibit normal epidermis and resultant secreted cuticle, defects lie in internal tissues. Somatic muscle detach and round up. Gut morphogenesis is defective: anterior midgut does not become a slender tube and only two fat gastric caecae are formed. The ventral nerve cord does not fully condense.

      (Bloor and Brown, 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescued by

      ifB6 is partially rescued by if+t39

      (Brown, 1994)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Selected as: F1 screen for mutations that fail to complement if3.

      (Bloor and Brown, 1998)
      Comments
      Comments

      Class 0 mutation.

      (Bloor and Brown, 1998)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ifB6
      Name Synonyms
      Secondary FlyBase IDs
        References (2)