FB2024_03 , released June 25, 2024
Allele: Dmel\abo2
Open Close
General Information
Symbol
Dmel\abo2
Species
D. melanogaster
Name
FlyBase ID
FBal0039123
Feature type
allele
Associated gene
Dmel\abo
Associated Insertion(s)
P{ry11}abo2
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Tomkiel et al., 1995)
P-element activity
(Berloco et al., 1995)
Progenitor genotype
Associated Insertion(s)
P{ry11}abo2
Cytology
Description

The abo2 mutation is due to an P{ry11} insertion in the intron 1 before the ATG start.

(Berloco et al., 2001)

No evidence for a blood element associated with abo1 or abo2.

(Tomkiel et al., 1995)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous mothers produce embryos that complete blastoderm formation, form cuticle but fail to hatch.

      (Tomkiel et al., 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Frequency of nondisjunction in abo1/subDub is double that of subDub/+, however no increase in nondisjunction is observed in abo2/sub females, suggesting that the interaction of subDub with abo1 is allele specific or due to a locus elsewhere on the chromosome.

      (Moore et al., 1994)

      ry+ is capable of conferring a wild type eye colour. Reversion of the mutant phenotype is accompanied by loss of the P{ry11}.

      (Tomkiel et al., 1995)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      abo2
      (Berloco et al., 1995)
      abo2
      Name Synonyms
      Secondary FlyBase IDs
        References (4)