FlyBase Allele Report: Dmel\rho[Stg]

General Information

Symbol

Dmel\rho^Stg

Species

D. melanogaster

Name

Strong

FlyBase ID

FBal0035904

Feature type

allele

Associated gene

Dmel\rho

Associated Insertion(s)

P{HS-rho}Stg

Carried in Construct

Also Known As

rho^HS-Stg, hs-rho^30a

Key Links

Allele class

gain of function allele

Mutagen

P-element activity

Nature of the Allele

Allele class

gain of function allele

(Sturtevant and Bier, 1995, Sturtevant et al., 1993)

Mutagen

P-element activity

(Sturtevant et al., 1993)

Progenitor genotype

rho^hs.PSt

(Sturtevant et al., 1993)

Associated Insertion(s)

P{HS-rho}Stg

Cytology

Description

rho gene expression is driven by an Hsp70 promoter.

(Sturtevant et al., 1993)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible

(Iyadurai et al., 2008, Baker et al., 2002)

visible | dominant

(Sturtevant et al., 1993)

visible | recessive

(Baonza and Garcia-Bellido, 1999)

Phenotype Manifest In

wing

(Baker et al., 2002)

wing | ectopic

(Iyadurai et al., 2008)

wing vein

(Baonza and Garcia-Bellido, 1999, Sturtevant et al., 1993)

wing vein | ectopic

(Marenda et al., 2006, Yu et al., 1996)

Detailed Description

Statement

Reference

Flies carrying rho^Stg show the formation of extra veins in the wing.

(Iyadurai et al., 2008)

rho^Stg mutants exhibit extra wing veins.

(Marenda et al., 2006)

Flies carrying rho^Stg have wing blisters (in the absence of heat shock).

(Baker et al., 2002)

rho^Wk/rho^Stg flies have extra wing veins.

(Baonza and Garcia-Bellido, 1999)

One copy causes a strong ectopic wing vein phenotype.

(Yu et al., 1996)

In the absence of heat induction individuals display a very strong constitutive excess vein phenotype.

(Sturtevant et al., 1993)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

rho^Stg has visible phenotype, enhanceable by msk⁴

(Baker et al., 2002)

rho^Stg/rho^Wk has visible phenotype, enhanceable by emc¹/emc¹¹

(Baonza and Garcia-Bellido, 1999)

Suppressed by

Statement

Reference

rho^Stg has visible phenotype, suppressible by Gl[+]/DCTN1-p150^Gl-1

(Iyadurai et al., 2008)

rho^Stg/rho^Wk has visible phenotype, suppressible by emc^D/emc^D

(Baonza and Garcia-Bellido, 1999)

Phenotype Manifest In

Enhanced by

Statement

Reference

rho^Stg has wing vein phenotype, enhanceable by msk⁵

(Marenda et al., 2006)

rho^Stg has wing phenotype, enhanceable by msk⁴

(Baker et al., 2002)

rho^Stg/rho^Wk has wing vein | ectopic phenotype, enhanceable by emc¹/emc¹¹

(Baonza and Garcia-Bellido, 1999)

Suppressed by

Statement

Reference

rho^Stg has wing | ectopic phenotype, suppressible by Gl[+]/DCTN1-p150^Gl-1

(Iyadurai et al., 2008)

rho^Stg/rho^Wk has wing vein | ectopic phenotype, suppressible by emc^D/emc^D

(Baonza and Garcia-Bellido, 1999)

rho^Stg has phenotype, suppressible by sog^EP3

(Yu et al., 1996)

rho^Stg has wing vein | ectopic phenotype, suppressible by sog^EP2

(Yu et al., 1996)

rho^Stg has wing vein | ectopic phenotype, suppressible by Dp(1;Y)sog⁺

(Yu et al., 1996)

rho^Stg has wing vein | ectopic phenotype, suppressible by dpp^s1

(Yu et al., 1996)

Additional Comments

Genetic Interactions

Statement

Reference

The extra wing vein phenotype caused by rho^Stg is partially suppressed by Gl¹/+.

(Iyadurai et al., 2008)

Transheterozygous rho^Stg/msk⁵ wings exhibit a strong enhancemnet of the rho^Stg extra-vein phenotype.

(Marenda et al., 2006)

The rho^Wk/rho^Stg extra wing vein phenotype is slightly enhanced by emc¹/emc¹¹ and slightly suppressed by emc^D/emc^D.

(Baonza and Garcia-Bellido, 1999)

rho^Stg extra wing vein phenotype is suppressed by sog^EP2, an extra copy of sog⁺ (Dp(1;Y)sog⁺) and dpp^s1.

(Yu et al., 1996)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Phenotype dependent on site of insertion of P{HS-rho} into the genome.

(Sturtevant et al., 1993)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

rho^HS-Stg

(Yu et al., 1996, Sturtevant and Bier, 1995)

rho^Stg

ve^Stg

Name Synonyms

Strong

(Sturtevant et al., 1993)

Secondary FlyBase IDs

References (7)

Report Sections

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