FB2024_03 , released June 25, 2024
Allele: Dmel\mystZa
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General Information
Symbol
Dmel\mystZa
Species
D. melanogaster
Name
FlyBase ID
FBal0035241
Feature type
allele
Associated gene
Dmel\mys
Associated Insertion(s)
Carried in Construct
P{mys+10.5}
Key Links
Transgenic product class
genomic_DNA
(Zusman et al., 1993)
wild_type
(Zusman et al., 1993)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Zusman et al., 1993)
wild_type
(Zusman et al., 1993)
Mutagen
in vitro construct
(Grinblat et al., 1994, Zusman et al., 1993)
Progenitor genotype
Carried in construct
P{mys+10.5}
Cytology
Description

10.5kb genomic fragment extending from a XhoI site upstream of mys to a point 200bp downstream of the second SmaI site in the 3' untranslated region of mys.

(Zusman et al., 1993)
Allele components
Component
Use(s)
Regulatory region(s)
mys
Encoded product / tool
mys
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      mystZa rescues mys11

      (Li et al., 1998)
      Partially rescues

      mystZa partially rescues mys11

      (Grinblat et al., 1994)

      mystZa partially rescues mys8

      (Grinblat et al., 1994)

      mystZa partially rescues mys11

      (Zusman et al., 1993)

      mystZa partially rescues mys8

      (Zusman et al., 1993)
      Comments

      Rescues the clone phenotypes of mys11 in the wing and the eye and the temperature-dependent wing phenotype of mys8, but cannot rescue the lethality of mys11 because the level of expression is reduced compared to wild type.

      (Grinblat et al., 1994)

      Rescues postembryonic phenotypes (wing blisters, disorganized photoreceptors and held-out wings) of mys11 and mys8. One copy rescues the dorsal hole phenotype of mys11 embryos, but these embryos rarely hatch. Two copies rescue embryonic development; the embryos hatch and have normal larval morphology, but are not rescued to adulthood.

      (Zusman et al., 1993)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Construct can functionally replace endogenous mys expression in most embryonic processes.

      (Li et al., 1998)

      mys rescue construct.

      (Grinblat et al., 1994)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      mys+t10.5
      mystGa
      mystZa
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0035240
      References (3)