FB2024_03 , released June 25, 2024
Allele: Dmel\Ubx195rx1
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General Information
Symbol
Dmel\Ubx195rx1
Species
D. melanogaster
Name
FlyBase ID
FBal0030339
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Mutagen
Nature of the Allele
Progenitor genotype
Cytology
Description

Approximately 11kb insertion in a EcoRI/HindIII fragment that includes two Ubx transcription start sites.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Characteristic null Ubx phenotype. Homo- and hemizygotes show parasegments 5 and 6 transformed to parasegment 4 and slight thoracic transformation of abdominal segments A2 to A7. In clonal analysis Ubx195rx1 tissue looks as for pre-existing Ubx null alleles. Transheterozygous combinations with many different classes of Ubx mutation, and wild type indicate that Ubx195rx1 hyperactivates the homologous Ubx gene. Effect is pairing-dependent. Mutation has strong positive effect on transvection, which, unlike other cases of transvection in Ubx, is not zeste-dependent.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Ubx195rx1
Name Synonyms
Secondary FlyBase IDs
    References (2)