FB2024_03 , released June 25, 2024
Allele: Dmel\wbHG10
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General Information
Symbol
Dmel\wbHG10
Species
D. melanogaster
Name
FlyBase ID
FBal0018459
Feature type
allele
Associated gene
Dmel\wb
Associated Insertion(s)
Carried in Construct
Also Known As
l(2)br1HG10
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Ashburner et al., 1999.10.12)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous embryos become abnormal during gastrulation; the germband twists and extends laterally rather than extending dorsally as in wild-type embryos. Significant gaps are seen in the dorsal trunk of the trachea. Somatic myotubes are often not attached to target epidermal attachment sites. This defect is most commonly seen in the ventral oblique muscles located in the anterior most segments of the embryo. Random disorganisation of myotubes and areas without myotubes are also occasionally seen.

      (Martin et al., 1999)

      Lethal in combination with Df(2L)fn7.

      (Gubb et al., 1985)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      G. Johnson.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      l(2)br1HG10
      (Gubb et al., 1985, Ashburner et al., 1982)
      wbHG10
      (Wolfstetter et al., 2019, Wolfstetter and Holz, 2012)
      Name Synonyms
      Secondary FlyBase IDs
        References (7)