FB2024_03 , released June 25, 2024
Allele: Dmel\UbxUab-1
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General Information
Symbol
Dmel\UbxUab-1
Species
D. melanogaster
Name
FlyBase ID
FBal0017570
Feature type
allele
Associated gene
Dmel\Ubx
Associated Insertion(s)
Carried in Construct
Also Known As
Uab1
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
Progenitor genotype
Caused by aberration
In(3R)iab9Uab1
Cytology
Description

-14 kb; +185 kb inverted; Bender, Akam, Karch, Beachy, Peifer, Spierer, Lewis, and Hogness (1983)

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Hemizygotes display transformation of posterior haltere towards wing, loss of first abdominal tergite and appearance of one or two legs from the first abdominal segment. In late embryos and larvae ventral setal belt of the first abdominal segment is transformed toward that of the third thoracic segment. Ventral pits and Keilin organs appear on abdominal segments A1 to A7, inclusive.

      (Bender et al., 1985)

      Causes A1 to transform toward A2. Reversion studies show that UbxUab-1 causes abnormal expression of abd-A domain functions in A1.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Lewis.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Uab1
      (Packert and Kuhn, 2003, Lloyd, 2000, Mathog, 1990, Bender et al., 1985)
      UbxUab-1
      Name Synonyms
      Secondary FlyBase IDs
        References (11)