FB2024_03 , released June 25, 2024
Allele: Dmel\Ubxbxd-K
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General Information
Symbol
Dmel\Ubxbxd-K
Species
D. melanogaster
Name
FlyBase ID
FBal0017559
Feature type
allele
Associated gene
Dmel\Ubx
Associated Insertion(s)
gypsy{}Ubxbxd-K
Carried in Construct
Also Known As
bxdK
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
(Lindsley and Zimm, 1992, Bender et al., 1983)
Progenitor genotype
Associated Insertion(s)
gypsy{}Ubxbxd-K
Cytology

Polytene chromosomes normal.

(Lindsley and Zimm, 1992)
Description

Insertion of a gypsy element.

(Castelli-Gair et al., 1992)

Insertion of gypsy element.

(Mathog, 1990)

Insertion of a gypsy element. The direction of transcription of the gypsy element is opposite to the direction of transcription of Ubx.

(Micol et al., 1990)

Insertion of a gypsy element at map position -2.5kb.

(Bender et al., 1983)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Transformation of posterior portion of haltere toward wing, replacement of A1 tergite by post-notal tissue, no extra legs. A1 setal belt is intermediate between A1 and T3 type belts. Ventral pits on all abdominal segments.

      (Lindsley and Zimm, 1992)

      Ubxbxd-K/Df(3R)Ubx109 flies show variable loss of the first abdominal tergite and the posterior haltere is variably enlarged. These flies do not have extra legs.

      (Bender et al., 1983)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      Ubxbxd-K has phenotype, suppressible by su(Hw)unspecified

      (Bender et al., 1983)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Kuhn.

      (Lindsley and Zimm, 1992)
      Comments
      Comments

      A 3.4kb repetitive element is inserted at map position -6.5kb but is probably not responsible for the mutant phenotype, as Ubxbxd-K is completely suppressible by mutations in su(Hw).

      (Bender et al., 1983)

      The phenotype of a number of combinations of Ubx mutations has been investigated to determine the role of the bxd regulatory region in the modulation of Ubx expression.

      (Castelli-Gair et al., 1992)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Ubxbxd-K
      bxdK
      (Duncan, 2002, Casares et al., 1997, Mathog, 1990, Micol et al., 1990, Bender et al., 1983)
      bxdk
      (Castelli-Gair et al., 1992, Lipshitz et al., 1987)
      Name Synonyms
      Secondary FlyBase IDs
        References (8)