FB2024_03 , released June 25, 2024
Allele: Dmel\SxlfPRC1
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General Information
Symbol
Dmel\SxlfPRC1
Species
D. melanogaster
Name
FlyBase ID
FBal0016700
Feature type
allele
Associated gene
Dmel\Sxl
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Lindsley and Zimm, 1992)
Mutagen
PM hybrid dysgenesis
(Lindsley and Zimm, 1992, Salz et al., 1987)
Progenitor genotype
SxlfPb
(Lindsley and Zimm, 1992, Salz et al., 1987)
Caused by aberration
Df(1)SxlfPRC1
Cytology
Description

Deletion of sequences extending proximally away from Sxl. Some P-element sequences remain.

(Salz et al., 1987)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Partial loss of function allele. Does not complement Sxlf1. Partially complements Sxl alleles that are defective in somatic function, suggesting that this allele retains some somatic function. Partially complements Sxlf2, an allele defective in germline function; heteroallelic females are semi-fertile and the ovaries do not contain any abnormal oocytes.

      (Salz et al., 1987)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      The failure of SxlfPRC1 to complement Sxlf1 shows that sequences proximal to coordinate 0 (coordinates according to FBrf0042036) are required for wild-type Sxl activity.

      (Salz et al., 1987)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      SxlfPRC1
      SxlfRC1
      (Lindsley and Zimm, 1992, Salz et al., 1987)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)