FB2024_03 , released June 25, 2024
Allele: Dmel\ScrWrv5
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General Information
Symbol
Dmel\ScrWrv5
Species
D. melanogaster
Name
FlyBase ID
FBal0015301
Feature type
allele
Associated gene
Dmel\Scr
Associated Insertion(s)
Carried in Construct
Also Known As
ScrScxWrv5, ScxW+Rx5
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Rogers et al., 1997, Gorman and Kaufman, 1995, Pattatucci et al., 1991, Scott et al., 1983)
Mutagen
X ray
(Pattatucci et al., 1991, Hazelrigg and Kaufman, 1983, Scott et al., 1983)
Progenitor genotype
ScrW
(Lindsley and Zimm, 1992, Pattatucci and Kaufman, 1991, Pattatucci et al., 1991, Hazelrigg and Kaufman, 1983)
Caused by aberration
In(3R)ScrWrv5
Cytology
Description

Inversion breakpoint is within the 5' end of the Scr transcription unit.

(Gorman and Kaufman, 1995)

Distal inversion breakpoint is at map position +45-52.

(Scott et al., 1983)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Scr8/ScrWrv5 transheterozygous pharate adults dissected from the pupal case exhibit ectopic wing formation in the dorsal anterior region of the prothorax, just ventral to the tergite in the dorsal pleuron. A normal wing forms in the mesothorax.

      (Rogers et al., 1997)

      Heterozygotes have a reduced number of sex comb teeth on the first tarsal segment of the prothoracic leg in males. Homozygotes show failure of head involution. Labial to maxillary transformation in the adult head and prothoracic to mesothoracic transformation in the adult thorax.

      (Pattatucci et al., 1991)

      There is a slight penetrance and expressivity of the 'Scx' phenotype: extra sex combs are seen on the meso- and metathoracic legs.

      (Hazelrigg and Kaufman, 1983)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      ScrScxWrv5
      (Gorman and Kaufman, 1995, Pattatucci and Kaufman, 1991, Pattatucci et al., 1991)
      ScrWrv5
      ScxW+RX5
      (Hazelrigg and Kaufman, 1983, Scott et al., 1983)
      ScxW+Rx5
      (Pattatucci et al., 1991)
      Name Synonyms
      Secondary FlyBase IDs
        References (7)