FB2024_03 , released June 25, 2024
Allele: Dmel\Pur331
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General Information
Symbol
Dmel\Pur331
Species
D. melanogaster
Name
FlyBase ID
FBal0014014
Feature type
allele
Associated gene
Dmel\Pu
Associated Insertion(s)
P{}Pur331
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
(Mackay et al., 1985)
Progenitor genotype
Associated Insertion(s)
P{}Pur331
Cytology

Polytene chromosomes normal.

(McLean et al., 1990, O'Donnell et al., 1989)
Description

Insertion of DNA.

(McLean et al., 1993)

GTP CH activity in Pur331/Pu+ same as wild type; somewhat reduced in homozygotes.

(Lindsley and Zimm, 1992)

P element insert in the eye specific region.

(McLean et al., 1990)

Mutation in the head specific region.

(O'Donnell et al., 1989)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Intermediate allele with respect to eye colour phenotype.

      (Lindsley and Zimm, 1992)

      Homozygous viable.

      (O'Donnell et al., 1989)

      Homozygous viable. Eye specific allele.

      (Reynolds and O'Donnell, 1987)

      Eye colour: pale orange to eyes with more pigmentation that can only be distinguished from wild-type in very young flies. Reduced pteridine levels in the head.

      (Mackay et al., 1985)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Finnerty.

      (Lindsley and Zimm, 1992)
      Comments
      Comments

      GTP cyclohydrolase activity is strongly reduced in the adult head, nearly normal in the adult body and moderately reduced in the prepupa of homozygotes. The viability and in trans with other Pu alleles has been determined.

      (Mackay et al., 1985)

      Class I Pu allele.

      (Reynolds and O'Donnell, 1987)

      Class I allele: eye specific phenotypes.

      (O'Donnell et al., 1989)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Pu331
      (Reynolds and O'Donnell, 1987)
      Pur331
      (Weisberg and O'Donnell, 1986)
      Name Synonyms
      Secondary FlyBase IDs
        References (9)