FB2024_03 , released June 25, 2024
Allele: Dmel\ptg7
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General Information
Symbol
Dmel\ptg7
Species
D. melanogaster
Name
FlyBase ID
FBal0013999
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The response of homozygous flies to benzaldehyde is lower than wild-type in an olfactory jump assay, although the response to ethyl acetate and propionic acid is normal. The cuticle is marked by a discrete patch of hyperpigmentation on the mesonotum of the dorsal thorax, which appears as a pentagonal spot from which three narrow stripes of pigmentation extend anteriorly, resembling a trident. This phenotype is more severe in females. Homozygous females have low fertility; they lay normal numbers of eggs, but only 10-20% undergo fertilisation and normal embryonic development. ptg2 fails to complement ptg7 in the olfactory jump assay, and with respect to pigmentation. ptg4 fails to complement ptg7 in the olfactory jump assay, but complements the pigmentation phenotype.

Responds defectively to benzaldehyde but normally to ethyl acetate across a broad range of stimulus concentrations in the chemosensory jump assay.

Fertility of homozygotes low; response to odor of benzaldehyde reduced.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

The reduced female receptivity phenotype of Nrgibx is complemented by ptg7.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

Helfand, Carlson.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (4)