FB2024_03 , released June 25, 2024
Allele: Dmel\pll9
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General Information
Symbol
Dmel\pll9
Species
D. melanogaster
Name
FlyBase ID
FBal0013863
Feature type
allele
Associated gene
Dmel\pll
Associated Insertion(s)
Carried in Construct
Also Known As
pll864
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Tearle and Nusslein-Volhard, 1987)
Progenitor genotype
Cytology
Description

Amino acid replacement: E255K.

(Towb et al., 2001)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:27,252,137..27,252,137 [-]
Nucleotide change:

G27252137A

Amino acid change:

E255K | pll-PA; E255K | pll-PB

Reported amino acid change:

E255K

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Towb et al., 2001)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Stronger dorsalising phenotype at 18oC than 29oC. Transheterozygotes with pll4 are moderately dorsalised, the phenotype of pll4 Tl3p/pll9 is unchanged from the transheterozygote. Heterozygotes produced some dorsalised phenotypes at 29oC when also heterozygous for Df(3R)XM3.

      (Hecht and Anderson, 1993)

      pll4/pll9 is a cold sensitive combination. Cold sensitive period for pelle function is around stage 4 of development, coinciding with the nuclear import of dorsal protein.

      (Shelton and Wasserman, 1993)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Weak pll allele.

      (Hecht and Anderson, 1993)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      pll864
      (Towb et al., 2001, Hecht and Anderson, 1993, Shelton and Wasserman, 1993, Tearle and Nusslein-Volhard, 1987)
      pll9
      Name Synonyms
      Secondary FlyBase IDs
        References (6)