FB2024_03 , released June 25, 2024
Allele: Dmel\pll3
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General Information
Symbol
Dmel\pll3
Species
D. melanogaster
Name
FlyBase ID
FBal0013857
Feature type
allele
Associated gene
Dmel\pll
Associated Insertion(s)
Carried in Construct
Also Known As
pll074, pll74
Key Links
Genomic Maps

Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Belvin et al., 1995)
Mutagen
ethyl methanesulfonate
(Tearle and Nusslein-Volhard, 1987)
Progenitor genotype
Cytology
Description

Amino acid replacement: Y332N.

(Towb et al., 2001)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:27,251,843..27,251,843 [-]
Nucleotide change:

T27251843A

Amino acid change:

Y332N | pll-PA; Y332N | pll-PB

Reported amino acid change:

Y332N

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Towb et al., 2001)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes and heterozygotes with pll2 produce strongly dorsalised embryos. Heterozygotes with pll1 produce moderately dorsalised embryos.

      (Hecht and Anderson, 1993)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Double mutant combinations with eaD1 are strongly dorsalized.

      (Chasan et al., 1992)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Strong pll allele.

      (Hecht and Anderson, 1993)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      74
      (Riede, 2001)
      pll074
      (Towb et al., 2001, Misra et al., 1998, Hecht and Anderson, 1993)
      pll3
      pll74
      (Belvin et al., 1995, Chasan et al., 1992, Tearle and Nusslein-Volhard, 1987)
      Name Synonyms
      Secondary FlyBase IDs
        References (9)