FB2024_03 , released June 25, 2024
Allele: Dmel\Pcl7
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General Information
Symbol
Dmel\Pcl7
Species
D. melanogaster
Name
FlyBase ID
FBal0013614
Feature type
allele
Associated gene
Dmel\Pcl
Associated Insertion(s)
Carried in Construct
Also Known As
PclE90
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Tearle and Nusslein-Volhard, 1987)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Heterozygous males do not have ectopic sex combs on the second and third legs.

      (Qi et al., 2006)

      Dominant extra sex comb phenotype.

      (Jurgens, 1985)

      leg2, leg3 transformed to leg1 (het)

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Pcl7/Pcl[+] is a suppressor of visible | dominant | homeotic phenotype of brm[+]/brm2, trxE2

      (Gildea et al., 2000)

      Pcl7/Pcl[+] is a suppressor of visible | dominant | homeotic phenotype of ash117, trxB11/trx[+]

      (Gildea et al., 2000)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Pcl7/Pcl[+] is a suppressor of adult metathoracic segment phenotype of brm[+]/brm2, trxE2

      (Gildea et al., 2000)

      Pcl7/Pcl[+] is a suppressor of adult metathoracic segment phenotype of ash117, trxB11/trx[+]

      (Gildea et al., 2000)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      rept06945 shows little or no interaction (in terms of ectopic sex comb phenotype) when in double heterozygous combination with Pcl7.

      (Qi et al., 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Struhl.

      Comments
      Comments

      Weak derepression of en expression.

      (Moazed and O'Farrell, 1992)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      References (9)