FB2024_03 , released June 25, 2024
Allele: Dmel\mam23
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General Information
Symbol
Dmel\mam23
Species
D. melanogaster
Name
FlyBase ID
FBal0012031
Feature type
allele
Associated gene
Dmel\mam
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Hyperplasia of replicating sensory precursors: due to an increased number of ectodermal cells being recruited as sensory precursor cells. Extra precursor cells are recruited beyond the normal time window for neurogenesis in the PNS.

      (Bodmer et al., 1993)

      Strong allele.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      mam23/mam[+] is a suppressor | partially of visible phenotype of EndoGIUAS.cOa, Scer\GAL4en-e16E

      (O'Keefe et al., 2011)
      Phenotype Manifest In
      NOT Enhancer of
      Statement
      Reference

      mam23 is a non-enhancer of larval intersegmental nerve | heat sensitive phenotype of Nl1N-ts1

      (Crowner et al., 2003)
      Suppressor of
      Statement
      Reference

      mam23/mam[+] is a suppressor | partially of wing vein phenotype of EndoGIUAS.cOa, Scer\GAL4en-e16E

      (O'Keefe et al., 2011)
      NOT Suppressor of
      Statement
      Reference

      mam23 is a non-suppressor of larval intersegmental nerve | heat sensitive phenotype of Nl1N-ts1

      (Crowner et al., 2003)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      mam23/+ partially rescues the loss of wing vein caused by expression of EndoGIScer\UAS.cOa under the control of Scer\GAL4en-e16E.

      (O'Keefe et al., 2011)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Wetter.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      mam23
      (O'Keefe et al., 2011)
      mamz14
      Name Synonyms
      Secondary FlyBase IDs
        References (3)