FB2024_03 , released June 25, 2024
Allele: Dmel\Orc52
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General Information
Symbol
Dmel\Orc52
Species
D. melanogaster
Name
FlyBase ID
FBal0008429
Feature type
allele
Associated gene
Dmel\Orc5
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Ashburner et al., 1999.10.12)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Orc52/Df(2L)b84a9 mutants show replication defects, abnormally condensed chromosomes and a metaphase-like arrest.

      (Pflumm and Botchan, 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      Orc51

      (Pflumm and Botchan, 2001)
      Rescued by

      Orc51/Orc52 is rescued by Orc5+tPa

      (Pflumm and Botchan, 2001)
      Not rescued by

      Orc51/Orc52 is not rescued by Orc5Δ

      (Pflumm and Botchan, 2001)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      Lindsley.

      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      64-480
      Orc52
      l(2)34Df2
      (Ashburner et al., 1999.10.12, Iyengar et al., 1999)
      l(2)34DfL480
      (Pflumm and Botchan, 2001, Roote, 2001.5.23)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)