FB2024_03 , released June 25, 2024
Allele: Dmel\cacL13
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General Information
Symbol
Dmel\cacL13
Species
D. melanogaster
Name
FlyBase ID
FBal0006133
Feature type
allele
Associated gene
Dmel\cac
Associated Insertion(s)
Carried in Construct
Also Known As
l(1)L13
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
(Kulkarni and Hall, 1987)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      dorsal medial muscle & synapse (with cacTS2)

      (Kawasaki et al., 2000)

      retina

      (Smith et al., 1998)
      Detailed Description
      Statement
      Reference

      General characteristics of mutant phenotype (heterozygous with a viable allele): Song pulse - mutant; Optomotor test - mutant; CC-phototaxis - mutant; Y-phototaxis - mutant; ERG transients - mutant; ERG LCRP amplitude - mutant; ERG LCRP kinetics - mutant; ERG Rebound - mutant; ERG refractory wandering - mutant.

      (Smith et al., 1998)

      Song pulse amplitude in heterozygotes with cac1 is higher than wild type.

      (Kulkarni and Hall, 1987)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      cacTS2

      (Dellinger et al., 2000)

      cacTS2

      (Kawasaki et al., 2000)

      cac1

      (Kulkarni and Hall, 1987)

      cacEE171

      (Kulkarni and Hall, 1987)
      Comments

      cacL13 fails to complement the cacTS2 electrophysiological phenotype.

      (Kawasaki et al., 2000)

      Extensive phenogenetic analysis of allelic combinations reveals a phenotypic series for visually mediated behaviors and genetically separable ERG defects and courtship song defects.

      (Smith et al., 1998)

      Failure to complement statements based on ERG phenotype (cacEE171) and singing behaviour (cac1).

      (Kulkarni and Hall, 1987)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Lefevre.

      Comments
      Comments

      Maternal germline clonal analysis demonstrates there is no maternal effect.

      (Perrimon et al., 1989)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (6)
      Reported As
      Symbol Synonym
      L13
      (Perrimon et al., 1989)
      cacL-13
      (Smith et al., 1998)
      cacL13
      l(1)11Aa1
      l(1)L13
      (Dellinger et al., 2000, Kawasaki et al., 2000, Kulkarni and Hall, 1987)
      nbAL13
      Name Synonyms
      Secondary FlyBase IDs
        References (7)