FB2024_03 , released June 25, 2024
Allele: Dmel\g4
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General Information
Symbol
Dmel\g4
Species
D. melanogaster
Name
FlyBase ID
FBal0004961
Feature type
allele
Associated gene
Dmel\g
Associated Insertion(s)
?{}g4
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
Progenitor genotype
Associated Insertion(s)
?{}g4
Cytology
Description

A 24-bp deletion that spans an intron-exon junction and results in a frame shift in the g-RB and g-RD transcripts, and also ablates the ATG start codon of the g-RF transcript.

(Miller et al., 2016)

1kb insertion in g.

(Lloyd et al., 1999)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Eye colour: red pigments are reduced to 25 +/- 1% of wild-type levels, brown pigments are reduced to 28 +/- 5% of wild-type levels in females. Red pigments are reduced to 38 +/- 3% of wild-type levels, brown pigments are reduced to 37 +/- 3% of wild-type levels in males. Malpighian tubule colour: very pale-clear (wild-type colour is orange). Testis colour: yellow (wild-type colour is bright yellow).

      (Lloyd et al., 1999)

      22% normal red pigment and 23% normal brown pigment.

      (Nolte, 1959)

      Malpighian tubule colour: extremely pale yellow.

      (Brehme and Demerec, 1942)

      Eye colour: like g2. RK1.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhanced by
      Statement
      Reference

      g4 has abnormal eye color phenotype, non-enhanceable by E(z)1

      (Lloyd et al., 2002)
      Phenotype Manifest In
      NOT Enhanced by
      Statement
      Reference

      g4 has pigment cell phenotype, non-enhanceable by E(z)1

      (Lloyd et al., 2002)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The E(z)1 mutation does not affect levels of red pigment in the eye of g4 mutants.

      (Lloyd et al., 2002)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (28)
      Notes on Origin
      Discoverer

      Glass, 1929.

      Induced on: In(1)dl-49.

      Comments
      Comments

      Complements: l(1)dd4xr16

      (Barbosa et al., 2000)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      g4
      (Miller et al., 2016)
      Name Synonyms
      Secondary FlyBase IDs
        References (12)