FB2024_03 , released June 25, 2024
Aberration: Dmel\Ab(1)oss
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General Information
Symbol
Ab(1)oss
Species
D. melanogaster
Name
FlyBase ID
FBab0047685
Feature type
chromosome_structure_variation
Also Known As
oss
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to wild type)
chromosome_structure_variation
(Wang et al., 2014)
Class of aberration (relative to progenitor)
chromosome_structure_variation
(Wang et al., 2014)
Breakpoints
Causes alleles
upd1os-s
(Wang et al., 2014)
upd3os-s
(Wang et al., 2014)
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
upd3
(Wang et al., 2014)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations

    Ab(1)oss/Df(1)os1A2 mutant flies have small eyes compared to wild type. No wing defects are seen.

    (Wang et al., 2014)

    Df(1)os1/Ab(1)oss mutant flies have small eyes compared to wild type. No wing defects are seen.

    (Wang et al., 2014)

    Df(1)os1/Ab(1)oss flies have small eyes, but their wings are normal.

    (Verderosa and Muller, 1954)

    Df(1)oso/Ab(1)oss flies appear normal (no mutant wing or eye phenotypes are seen).

    (Verderosa and Muller, 1954)
    NOT in combination with other aberrations

    Ab(1)oss heterozygotes do not show significant changes in intestinal stem cell proliferation (phospho-H3 staining) in the adult midgut, as compared to controls.

    (Gultekin and Steller, 2019)

    Ab(1)oss (affecting both upd1, upd3) homozygous mutant adults present a significant decrease in the bacterial burden, and significant increases in the survival and hemocyte numbers upon infection with Mycobacterium marinum, as compared to wild-type controls; non-infected individuals present similar survival and hemocyte numbers as compared to wild-type controls.

    (Péan et al., 2017)

    Homozygous Ab(1)oss mutant flies have small eyes compared to wild type. No wing defects are seen.

    (Wang et al., 2014)
    Stocks (16)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    Complementation and expression data show that Ab(1)oss disrupts the function of upd1 and upd3, represented by the alleles upd1os-s and upd3os-s.

    (Wang et al., 2014)
    Synonyms and Secondary IDs (4)
    Reported As
    Symbol Synonym
    Ab(1)oss
    oss
    (Péan et al., 2017, Wang et al., 2014, Wang and Harrison, 2007, Wang et al., 2006, Tsai and Sun, 2004, Verderosa and Muller, 1954)
    sy
    (Verderosa and Muller, 1954)
    updos-s
    (Koh et al., 2023)
    Name Synonyms
    Secondary FlyBase IDs
    • FBal0013293
    References (9)