FB2024_03 , released June 25, 2024
Aberration: Dmel\Df(2L)x528
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General Information
Symbol
Df(2L)x528
Species
D. melanogaster
Name
FlyBase ID
FBab0041478
Feature type
chromosomal_deletion
Computed Breakpoints include
Features within 25E1--25E2
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
P{PZ}H-15
(Miskolczi-McCallum et al., 2005)
Mutagen
X ray
(Miskolczi-McCallum et al., 2005, Buescher et al., 2004)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Buescher et al., 2004)
Breakpoints

[];[]

(Buescher et al., 2004)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In this case, the "Export to Hitlist" button at left will also be disabled.
    Phenotypic Data
    In combination with other aberrations

    Df(2L)x528/Df(2L)Gpdh1-A is embryonic lethal and impacts founder cells for lateral transverse muscle 3, lateral transverse muscle 4, lateral oblique muscle 1 and ventral transverse muscle 1; loss of lateral transverse muscles.

    (Kumar et al., 2015)

    Inferred to overlap with: Df(2L)Gpdh1-A.

    (Kumar et al., 2015, Miskolczi-McCallum et al., 2005)

    Embryos trans-heterozygous for Df(2L)sc19-4 and Df(2L)x528 yield an abnormal neuronal cell fate specification phenotype identical to that observed for embryos homozygous for Df(2L)sc19-4.

    (Leal et al., 2009)

    Inferred to overlap with: Df(2L)sc19-4.

    (Leal et al., 2009)

    Df(2L)x528/Df(2L)Gpdh1-A embryos show a loss of neuroblasts NB1-1, NB2-5 and NB2-4. This loss is much more pronounced in odd-numbered than even-numbered abdominal segments. However, the loss is similar to mid mutants, suggesting that the it is deletion of the mid gene and not the H15 gene that is causing the phenotype.

    (Buescher et al., 2006)

    Df(2L)Gpdh1-A/Df(2L)x528 larvae show a loss of denticle belts; denticle rows 1 to 5 are frequently lost in odd-numbered segments, whereas even-numbered segments show milder defects.

    (Buescher et al., 2004)
    NOT in combination with other aberrations
    Stocks (0)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    Df(2L)x528
    (Kumar et al., 2015, Leal et al., 2009, Buescher et al., 2006)
    Name Synonyms
    Secondary FlyBase IDs
      References (6)