[57B3-57B3];[57B5-57B5];
A set of isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Initial set of 519 isogenic deletions provides 56% genome coverage.
The current Exelixis collection at the Bloomington Stock Center differs from the original described in FBrf0175003 : a significant number were shown not to carry a deletion and have been removed from the collection; a number of stocks have been lost; a number of additional deletions are included that were generated after publication.
57B3;57B7
57B3;57B5
Breakpoint based on release 3 sequence coordinate from Parks et al., 2004 (FBrf0174230), converted to release 5 coordinate.
Breakpoint from FlyBase's release 5 sequence location of progenitor insertion.
Df(2R)Exel7166 embryos have significantly reduced neuroblast and daughter proliferation in the brain and significantly reduced numbers of neuroblasts, including type II neuroblasts, compared to controls; this does not affect the anterior dorsomedial cluster.
Df(2R)Exel7166 heterozygotes show a dominant electrophysiological impairment in mini amplitude.
Dominantly modifies the size of pupae relative to wild-type controls.