FB2024_03 , released June 25, 2024
Aberration: Dmel\Df(3L)iro-2
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General Information
Symbol
Df(3L)iro-2
Species
D. melanogaster
Name
FlyBase ID
FBab0024878
Feature type
chromosomal_deletion
Also Known As
Df(3L)iro2, Df(3L)iro2, iro2, Df(3)iro2
Computed Breakpoints include

69B;69D1-69D6

Features within 69B--69D6
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
diepoxybutane
(Leyns et al., 1996)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Kehl et al., 1998, Gomez-Skarmeta et al., 1996, Leyns et al., 1996)
Breakpoints

69B;69D

(Kehl et al., 1998, Gomez-Skarmeta et al., 1996, Leyns et al., 1996)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << ara << caup << bk2

Genetic mapping information
Comments
Comments on Cytology

Limits of break 1 from polytene analysis (FBrf0086419) Left limit of break 2 from inclusion of ara (FBrf0086419) Right limit of break 2 from polytene analysis (FBrf0086419)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
ara
(Gomez-Skarmeta et al., 1996)
caup
(Gomez-Skarmeta et al., 1996)
eyg
(Aldaz et al., 2003)
mirr
(Collins and Cohen, 2005)
sti
(Shandala et al., 2004)
ver
(Carre et al., 2005)
vih
(Mathe et al., 2004)
Partially deleted / disrupted
Molecular Data
Completely deleted
sti
(Naim et al., 2004)
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In this case, the "Export to Hitlist" button at left will also be disabled.
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    The Df(3L)iro-2 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion).

    (Mason et al., 2004)

    Heterozygosity for Df(3L)iro-2 results in 8.5% X chromosome nondisjunction and 3.4% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.

    (Harris et al., 2003)

    Homozygous embryos have normal gut morphology.

    (Merabet et al., 2002)

    In female D.simulans/D.melanogaster hybrids heterozygous for Df(3L)iro-2 the anterior notopleural bristle, presutural bristle, posterior notopleural bristle, anterior postalar bristle, posterior dorsocentral bristle, anterior dorsocentral bristle, and the posterior postalar bristle are lost at a high frequency compared to female D.simulans/D.melanogaster hybrid controls, when grown at 25oC. At 18oC only the posterior supraalar bristle and the anterior supraalar bristle are affected.

    (Skaer and Simpson, 2000)

    Homozygous lethal.

    (Leyns et al., 1996)
    Stocks (3)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    Isolated as a mutation that alters the pattern of bristles when doubly heterozygous with Df(4)M101-62f.

    (Leyns et al., 1996)
    Synonyms and Secondary IDs (9)
    References (34)