FB2024_03 , released June 25, 2024
Aberration: Dmel\Df(3L)8ex25
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General Information
Symbol
Df(3L)8ex25
Species
D. melanogaster
Name
FlyBase ID
FBab0024864
Feature type
chromosomal_deletion
Also Known As
Df(3L)8ex25
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
P{lacW}Klc59A
(Desai et al., 1996)
Mutagen
Delta2-3 transposase
(Desai et al., 1996)
Class of aberration (relative to wild type)
chromosomal_deletion
Class of aberration (relative to progenitor)
Breakpoints
Causes alleles
Klc8ex25
(Desai et al., 1996)
Ptp69D8ex25
(Desai and Purdy, 2003, Sun et al., 2000, Desai et al., 1997, Desai et al., 1996)
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Ptp69D
(Desai et al., 1997)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Df(3L)8ex25/Ptp69D1 transheterozygotes are deleted for the entire Ptp69D gene.

    (Desai et al., 1997)
    Stocks (1)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    The Df(3L)8ex25 chromosome may act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but the eye colour phenotype in the presence of Df(3L)8ex25 overlaps the eye colour phenotype in a wild-type background so it cannot be unequivocally demonstrated that the deficiency chromosome uncovers a suppressor of telomeric silencing. In addition, any suppression is a false positive result (the suppressor is not within the bounds of the deficient region) because the region of the deficiency is covered by one or more nonsuppressing deficiencies.

    (Mason et al., 2004)
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Df(3L)8ex25
    (Agrawal and Hardin, 2016, Gassman et al., 2013, Lee et al., 2013, Jeon et al., 2008, Kurusu and Zinn, 2008, Sun et al., 2001)
    Df(3L)8ex25
    (Desai and Purdy, 2003, Desai et al., 1996)
    Name Synonyms
    Secondary FlyBase IDs
      References (14)